Description

4'-Hydroxy-3',4',5',6'-Tetrahydro-2'H-[2,4']Bipyridinyl-1'-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex bicyclic structure. This compound is critical for the synthesis of sophisticated active pharmaceutical ingredients (APIs) where precise molecular architecture is required. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug discovery.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for clinical and commercial manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	4'-Hydroxy-3',4',5',6'-Tetrahydro-2'H-[2,4']Bipyridinyl-1'-Carboxylic Acid tert-Butyl Ester
CAS No.	90606-75-0
Molecular Formula	C15H22N2O3
Molecular Weight	278.35 g/mol
Synonyms	tert-Butyl 4'-hydroxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-carboxylate; 1'-BOC-4'-hydroxy-1',2',3',4',5',6'-hexahydro-2,4'-bipyridine; 4'-Hydroxy-3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-carboxylic acid 1,1-dimethylethyl ester; BOC-Protected Hydroxy Bipyridine Derivative; 1,1-Dimethylethyl 4'-hydroxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-carboxylate
EINECS	Contact for details

Quality Control

Our 4'-Hydroxy-3',4',5',6'-Tetrahydro-2'H-[2,4']Bipyridinyl-1'-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.