Description

Ethyl 2-(Bromomethyl)Nicotinate Hydrochloride is a high-purity, versatile chemical building block essential for advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). Pharmaceutical R&D laboratories and fine chemical manufacturers need it for its reactive bromomethyl and ester functionalities, which facilitate critical carbon-carbon bond formation and heterocyclic modifications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nicotinic acid derivatives and complex heterocyclic compounds with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a tagging or cross-linking reagent for studying protein interactions and enzyme mechanisms due to its electrophilic bromomethyl group.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry laboratories and for custom synthesis projects.

Basic Information

Product Name	Ethyl 2-(Bromomethyl)Nicotinate Hydrochloride
CAS No.	90561-86-7
Molecular Formula	C9H11BrClNO2
Molecular Weight	280.55 g/mol
Synonyms	2-(Bromomethyl)nicotinic acid ethyl ester hydrochloride; Ethyl 2-(bromomethyl)-3-pyridinecarboxylate hydrochloride; 3-Pyridinecarboxylic acid, 2-(bromomethyl)-, ethyl ester, hydrochloride; Ethyl 2-bromomethylnicotinate HCl; Nicotinic acid, 2-(bromomethyl)-, ethyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Bromomethyl)Nicotinate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay, impurity profile, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.