Description

2-(Pyridin-3-Yl)Morpholine Dihydrochloride is a high-purity organic salt compound, primarily utilized as a key synthetic intermediate in advanced pharmaceutical research and development. Its value lies in its role as a versatile building block for constructing complex molecules, particularly in medicinal chemistry programs targeting central nervous system and other therapeutic areas. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates with morpholine and pyridine pharmacophores.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and the discovery of novel drug candidates for various disease targets.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Ligand and Catalyst Development: Used as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	2-(Pyridin-3-Yl)Morpholine Dihydrochloride
CAS No.	90533-86-1
Molecular Formula	C9H14Cl2N2O
Molecular Weight	237.13 g/mol
Synonyms	3-(Morpholin-4-yl)pyridine dihydrochloride; 2-(3-Pyridinyl)morpholine dihydrochloride; 4-(Pyridin-3-yl)morpholine dihydrochloride; 3-Morpholin-4-ylpyridine dihydrochloride; 3-Pyridylmorpholine dihydrochloride; N-(Pyridin-3-yl)morpholine dihydrochloride; 90533-86-1 (CAS)
EINECS	Contact for details

Quality Control

Our 2-(Pyridin-3-Yl)Morpholine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets stringent specifications for research and development use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.