Description

tert-Butyl 3-Hydroxybutanoate is a valuable chiral building block and protected intermediate in organic synthesis. This compound matters for its role in producing high-value pharmaceuticals and fine chemicals, where its tert-butyl ester group offers stability under various reaction conditions. It is needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in statin drugs and other therapeutics.
• Asymmetric Synthesis: Serves as a precursor for chiral β-hydroxy acids and esters used in catalytic asymmetric reactions.
• Fine Chemical Production: Employed in the manufacture of fragrances, flavors, and advanced polymeric materials.
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic chemistry and process optimization.

Basic Information

Product Name	tert-Butyl 3-Hydroxybutanoate
CAS No.	90435-23-7
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	3-Hydroxybutyric Acid tert-Butyl Ester; tert-Butyl 3-Hydroxybutyrate; (R/S)-tert-Butyl 3-Hydroxybutanoate; Butanoic acid, 3-hydroxy-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 3-hydroxybutanoate; 3-Hydroxybutanoic Acid tert-Butyl Ester; TBHB
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Hydroxybutanoate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess (if applicable), and impurity profiles are available upon request, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Specific Rotation (if chiral)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.