Description

7-Nitrobenzo[B]Thiophene-2-Carboxylic Acid is a high-purity, versatile heterocyclic building block and key synthetic intermediate. This compound is essential for advanced organic synthesis, particularly in the development of novel pharmaceuticals and functional materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds with thiophene-based scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its nitro and carboxylic acid functional groups for further derivatization.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-deficient aromatic system.
• Dye & Pigment Synthesis: Employed in the production of specialized dyes and pigments where the nitrobenzo[b]thiophene core imparts specific color and stability properties.
• Ligand & Catalyst Development: The carboxylic acid moiety allows for coordination to metals, making it useful for creating novel ligands and catalysts in asymmetric synthesis.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and exploratory research in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	7-Nitrobenzo[B]Thiophene-2-Carboxylic Acid
CAS No.	90407-22-0
Molecular Formula	C9H5NO4S
Molecular Weight	223.21 g/mol
Synonyms	7-Nitrobenzo[b]thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 7-nitrobenzo[b]-; 7-Nitro-2-benzothiophenecarboxylic Acid; 7-Nitrobenzo[b]thiophene-2-carboxylate; 7-Nitro-2-carboxybenzo[b]thiophene; 90407-22-0; 7-Nitrobenzo[b]thien-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Nitrobenzo[B]Thiophene-2-Carboxylic Acid is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.