Description

5-Bromopyridine-3,4-Dicarboxylic Acid is a high-purity brominated pyridine derivative serving as a critical multifunctional building block in advanced organic synthesis. This compound is valued for its ability to introduce both bromine and carboxylic acid functional groups, enabling precise molecular modifications and the construction of complex heterocyclic systems. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its halogen and acid functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Building Block: Employed in the synthesis of functionalized polymers, metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Biology Probe Synthesis: Utilized to create tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development of scalable synthetic routes.

Basic Information

Product Name	5-Bromopyridine-3,4-Dicarboxylic Acid
CAS No.	90325-36-3
Molecular Formula	C7H4BrNO4
Molecular Weight	246.02 g/mol
Synonyms	3,4-Pyridinedicarboxylic acid, 5-bromo-; 5-Bromo-3,4-pyridinedicarboxylic acid; 5-Bromopyridine-3,4-dicarboxylic acid; 5-Bromonicotinic acid-4-carboxylic acid; 5-Bromo-3,4-dicarboxypyridine; 90325-36-3 (CAS); 5-Br-Py-3,4-DCA (abbreviation)
EINECS	Contact for details

Quality Control

Our 5-Bromopyridine-3,4-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.