Description

2-Chloro-4-(1-Piperidinylcarbonyl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct heterocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific molecular framework serves as a key building block. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for creating complex molecular architectures in academic and industrial R&D labs.
• Ligand and Catalyst Preparation: Employed in the preparation of specialized ligands for metal-catalyzed reactions and coordination chemistry.
• Material Science: Potential intermediate for the synthesis of organic electronic materials and functional polymers.

Basic Information

Product Name	2-Chloro-4-(1-Piperidinylcarbonyl)Pyridine
CAS No.	90287-80-2
Molecular Formula	C11H13ClN2O
Molecular Weight	224.69 g/mol
Synonyms	2-Chloro-4-(piperidine-1-carbonyl)pyridine; 2-Chloro-4-piperidin-1-ylcarbonylpyridine; 4-(1-Piperidinylcarbonyl)-2-chloropyridine; 2-Chloro-4-(N-piperidinylcarbonyl)pyridine; 2-Chloro-4-(piperidin-1-ylcarbonyl)pyridine; 90287-80-2; 2-Chloro-4-(1-piperidylcarbonyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(1-Piperidinylcarbonyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be moisture-sensitive; keep the container tightly sealed when not in use. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.