Description

8 β-(Bis(2-Chloroethyl)Amino)-6,7-Didehydro-3-Hydroxy-17-Methyl-4,5 α-Epoxymorphinan is a highly specialized nitrogen mustard derivative of the morphinan class, designed for advanced research and development in medicinal chemistry. This compound is valued for its potential as a key synthetic intermediate in the exploration of novel therapeutic agents targeting specific receptor pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on oncology and neuropharmacology. Our supply ensures high purity and batch-to-batch consistency, which are critical for reliable experimental outcomes and process development.

Application

• Pharmaceutical Research Intermediate: Serves as a critical building block in the synthesis of novel drug candidates for preclinical studies.
• Medicinal Chemistry Exploration: Used to investigate structure-activity relationships (SAR) in the development of targeted therapies.
• Oncological Agent Development: Explored for its potential as a precursor to alkylating agents in experimental cancer research.
• Neuropharmacology Studies: Investigated for interactions with opioid receptor subtypes due to its morphinan core structure.
• Reference Standard: Employed as an analytical standard in method development and quality control for related compounds.
• Process Chemistry: Used in scale-up and optimization studies for the production of specialized active pharmaceutical ingredients (APIs).

Basic Information

Product Name	8 β-(Bis(2-Chloroethyl)Amino)-6,7-Didehydro-3-Hydroxy-17-Methyl-4,5 α-Epoxymorphinan
CAS No.	90246-16-5
Molecular Formula	C₂₃H₂₉Cl₂N₂O₃
Molecular Weight	452.39 g/mol
Synonyms	8β-[Bis(2-chloroethyl)amino]-6,7-didehydro-3-hydroxy-17-methyl-4,5α-epoxymorphinan; 8β-(N,N-Bis(2-chloroethyl)amino)-6,7-didehydro-3-hydroxy-17-methyl-4,5α-epoxymorphinan; 8β-(Bis(2-chloroethyl)amino)-6,7-didehydro-3-hydroxy-17-methyl-4,5α-epoxymorphinan; 8β-(N,N-Di(2-chloroethyl)amino)-6,14-ethenomorphinan-3-ol; Nitrogen mustard morphinan derivative; 90246-16-5; 8-β-(Bis(2-Chloroethyl)Amino)-6,7-Didehydro-3-Hydroxy-17-Methyl-4,5 α-Epoxymorphinan
EINECS	Contact for details

Quality Control

Our 8 β-(Bis(2-Chloroethyl)Amino)-6,7-Didehydro-3-Hydroxy-17-Methyl-4,5 α-Epoxymorphinan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.