Description

1,2,6-Trimethylpiperidin-4-Ol is a versatile piperidine derivative, a key chiral building block and intermediate in advanced organic synthesis. Its value lies in its functionalized structure, which provides a critical scaffold for constructing complex molecules with high stereochemical control. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor for the synthesis of various therapeutic agents, including central nervous system (CNS) drugs and analgesics.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its bioactive piperidine core.
• Catalyst and Ligand Preparation: Serves as a starting material for synthesizing specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of complex flavor and fragrance compounds, dyes, and other high-value specialty chemicals.
• Academic and R&D: A valuable reagent for medicinal chemistry research and process development in both industrial and university laboratories.

Basic Information

Product Name	1,2,6-Trimethylpiperidin-4-Ol
CAS No.	90226-91-8
Molecular Formula	C8H17NO
Molecular Weight	143.23 g/mol
Synonyms	4-Hydroxy-1,2,6-trimethylpiperidine; 1,2,6-Trimethyl-4-piperidinol; 1,2,6-Trimethyl-4-hydroxypiperidine; 4-Piperidinol, 1,2,6-trimethyl-; 1,2,6-Trimethylpiperidin-4-ol; 1,2,6-Trimethyl-4-piperidinol; 1,2,6-Trimethyl-4-piperidinol (cis/trans mixture)
EINECS	Contact for details

Quality Control

Our 1,2,6-Trimethylpiperidin-4-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from techniques such as GC, HPLC, NMR, and Karl Fischer titration. Our quality commitment ensures the material meets the stringent requirements for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 3.0%
Specific Rotation (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.