Description

2-Hydroxy-6-Methoxy-Isonicotinic Acid Methyl Ester is a specialized pyridine derivative that serves as a versatile and high-value synthetic intermediate. Its unique substitution pattern makes it a critical building block for constructing complex molecular architectures, particularly in advanced pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise and reliable intermediates for API synthesis and novel compound discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating complex chelating agents and ligands used in catalysis and material science.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and exploratory research in organic synthesis.

Basic Information

Product Name	2-Hydroxy-6-Methoxy-Isonicotinic Acid Methyl Ester
CAS No.	90222-65-4
Molecular Formula	C9H9NO4
Molecular Weight	195.17 g/mol
Synonyms	Methyl 2-hydroxy-6-methoxypyridine-4-carboxylate; 6-Methoxy-2-oxo-1,2-dihydropyridine-4-carboxylic acid methyl ester; 2-Hydroxy-6-methoxypyridine-4-carboxylic acid methyl ester; 4-Carbomethoxy-6-methoxy-2-pyridone; 2-Pyridone-4-carboxylic acid, 6-methoxy-, methyl ester
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-6-Methoxy-Isonicotinic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.