Description

(4-Methyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester CAS NO 90101-20-5 is a specialized Boc-protected pyridine derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a protected amine functionality on a pyridine scaffold, which is essential for constructing complex molecules with precise regiochemistry. This high-purity intermediate is indispensable for pharmaceutical R&D and fine chemical manufacturers engaged in developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Building block for creating advanced pesticides and herbicides with specific pyridine-based modes of action.
• Ligand & Catalyst Development: Precursor for nitrogen-containing ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: Used to incorporate pyridine motifs into peptide backbones to enhance stability and bioavailability.
• Material Science: Intermediate in the production of specialty polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Item	Details
Product Name	(4-Methyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	90101-20-5
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	tert-Butyl (4-methylpyridin-2-yl)carbamate; N-Boc-2-amino-4-methylpyridine; 2-((tert-Butoxycarbonyl)amino)-4-methylpyridine; Boc-2-Amino-4-methylpyridine; 4-Methyl-2-pyridinylcarbamic acid 1,1-dimethylethyl ester; 90101-20-5; (4-Methyl-2-pyridinyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of (4-Methyl-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester adheres to stringent quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring material for GMP intermediates and research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.