Description

Proline, 1,4-Dimethyl-5-Methylene- (7Ci) is a specialized, non-proteinogenic proline derivative characterized by its unique dimethyl and methylene substitutions on the pyrrolidine ring. This structural modification makes it a valuable chiral building block and intermediate for advanced organic synthesis, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for creating complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for peptidomimetics and enzyme inhibitors.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Fine Chemical Synthesis: Acts as a building block for creating complex natural product analogs, flavors, and fragrances.
• Biochemical Research: Employed in studies of enzyme mechanisms and as a probe for investigating proline metabolism and related biological pathways.
• Material Science: Potential monomer or modifier for creating specialty polymers with unique structural properties.

Basic Information

Product Name	Proline, 1,4-Dimethyl-5-Methylene- (7Ci)
CAS No.	90087-75-5
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	1,4-Dimethyl-5-methylenepyrrolidine-2-carboxylic acid; 5-Methylene-1,4-dimethyl-L-proline; (2S)-1,4-Dimethyl-5-methylenepyrrolidine-2-carboxylic acid; 1,4-Dimethyl-5-methyleneproline; Non-proteinogenic proline derivative; Dimethyl methyleneproline; CAS 90087-75-5
EINECS	Contact for details

Quality Control

Our Proline, 1,4-Dimethyl-5-Methylene- (7Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.