Description

4-Chloro-1-Oxy-Pyridine-2-Carboxylic Acid Methyl Ester is a versatile and high-purity pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its functionalized structure, which provides a reactive scaffold for constructing complex molecules in regulated industries. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical sectors, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug candidates targeting the central nervous system and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up services for fine chemical production.
• Academic and R&D Laboratories: Used in methodological research and as a reference standard in analytical chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Chloro-1-Oxy-Pyridine-2-Carboxylic Acid Methyl Ester
CAS No.	90048-09-2
Molecular Formula	C7H6ClNO3
Molecular Weight	187.58 g/mol
Synonyms	Methyl 4-chloro-1-oxidopyridine-2-carboxylate; Methyl 4-chloropyridine-1-oxide-2-carboxylate; 2-Pyridinecarboxylic acid, 4-chloro-1-oxide, methyl ester; 4-Chloro-2-(methoxycarbonyl)pyridine 1-oxide; 4-Chloropicolinic acid N-oxide methyl ester
EINECS	Contact for details

Quality Control

Our 4-Chloro-1-Oxy-Pyridine-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.