Description

Podophyllum Resin is a complex, standardized botanical extract derived from the roots of the *Podophyllum* plant, primarily *Podophyllum peltatum* (Mayapple). This natural resin is a critical precursor in the pharmaceutical industry for the semi-synthesis of potent chemotherapeutic agents. It serves as a vital raw material for manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require a reliable, high-purity source for API development and production.

Application

• Pharmaceutical API Synthesis: Primary use as a starting material for the semi-synthesis of anticancer drugs such as Etoposide, Teniposide, and Etopophos.
• Topical Formulations: Used in the preparation of topical solutions for the treatment of genital warts (condylomata acuminata).
• Biochemical Research: Serves as a source of podophyllotoxin and related lignans for studying tubulin polymerization inhibition and cell cycle arrest.
• Fine Chemical Intermediate: Utilized in the synthesis of novel derivatives and analogs for drug discovery and development programs.
• Reference Standard: Acts as a botanical reference standard in quality control laboratories for the identification and assay of podophyllum-based products.

Basic Information

Product Name	Podophyllum Resin
CAS No.	9000-55-9
Molecular Formula	Complex Mixture
Molecular Weight	N/A (Natural Product Extract)
Synonyms	Podophyllin; Podophyllum Resin; Podophyllotoxin Resin; Mayapple Resin; Mandrake Resin; Podofilox Resin; American Podophyllum Resin; Indian Podophyllum Resin
EINECS	Contact for details

Quality Control

Our Podophyllum Resin is produced and tested to meet stringent quality standards suitable for pharmaceutical use. Each batch is characterized for its podophyllotoxin content and related lignan profile. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and assay results. Quality systems are in place to ensure traceability and consistency, supporting compliance with cGMP and relevant pharmacopoeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Description	Amorphous powder or resin
Color	Light brown to brownish-yellow
Identification (IR)	Conforms to standard
Assay (Podophyllotoxin, HPLC)	40.0% - 50.0%
Loss on Drying	≤ 5.0 %
Residue on Ignition	≤ 1.0 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.