Description

Tributylchlorosilane is a versatile organosilicon reagent primarily used as a silylating agent and a key intermediate in organic synthesis. Its value lies in its ability to introduce the tributylsilyl protecting group, offering enhanced stability and selectivity in complex chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise protection of hydroxyl and other functional groups during multi-step synthesis.

Application

• As a protecting group reagent for hydroxyl (-OH) groups in complex organic and pharmaceutical synthesis.
• Key intermediate in the production of specialty silicone derivatives and functionalized silanes.
• Used in the synthesis of liquid crystals and other advanced electronic materials.
• Employed as a silylating agent in gas chromatography and mass spectrometry for derivatization of polar compounds.
• Facilitates nucleoside and carbohydrate chemistry by providing selective protection strategies.
• Precursor for catalysts and ligands used in homogeneous catalysis.
• Utilized in agrochemical research for the development of novel active ingredients.
• Building block for surface modification agents and adhesion promoters.

Basic Information

Product Name	Tributylchlorosilane
CAS No.	995-45-9
Molecular Formula	C₁₂H₂₇ClSi
Molecular Weight	234.88 g/mol
Synonyms	Chlorotributylsilane; Tributylsilyl chloride; TBSCI; n-Tributylchlorosilane; Silane, chlorotributyl-; Butylchlorosilane; NSC 60535
EINECS	213-619-8

Quality Control

Our Tributylchlorosilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 97.0%
Density (at 20°C)	0.88 - 0.90 g/mL
Refractive Index (n20/D)	1.450 - 1.455
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.