Description

Estradiol Valerate is a synthetic, long-acting ester derivative of the natural estrogen, estradiol. This compound is a critical active pharmaceutical ingredient (API) valued for its enhanced stability and prolonged duration of action compared to its parent hormone. It is primarily utilized in the pharmaceutical industry for the formulation of hormone replacement therapies (HRT) and various other therapeutic agents. Global B2B buyers rely on a consistent supply of high-purity Estradiol Valerate CAS NO 979-32-8 to ensure the efficacy and safety of their final medicinal products.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable hormone replacement therapies for managing menopausal symptoms.
• Hormone Therapy Formulations: Key component in combination drugs for treating estrogen deficiency, hypogonadism, and certain types of cancer.
• Veterinary Medicine: Used in veterinary pharmaceuticals for reproductive health management in animals.
• Research & Development: Serves as a reference standard and building block in endocrine research and the development of new therapeutic agents.
• Contraceptive Formulations: Employed in certain long-acting contraceptive preparations.

Basic Information

Product Name	Estradiol Valerate
CAS No.	979-32-8
Molecular Formula	C23H32O3
Molecular Weight	356.50 g/mol
Synonyms	Estradiol 17-Valerate; Estradiol Valerianate; 17β-Estradiol 17-Valerate; Delestrogen (Brand Name); Progynon Depot; Oestradiol Valerate; EV; (17β)-Estra-1,3,5(10)-triene-3,17-diol 17-pentanoate
EINECS	213-555-0

Quality Control

Our Estradiol Valerate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide detailed Certificates of Analysis (COA) that include data for identity, assay, purity, and specified impurities. Our quality commitment aligns with cGMP principles, and we can support documentation for regulatory submissions in global markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	+40° to +44° (c = 1 in dioxane)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.