Description

(8R,9S,13S,14S)-3,16-Dihydroxy-13-Methyl-7,8,9,11,12,14,15,16 Octahydro-6H-Cyclopenta[A]Phenanthren-17-One is a high-purity steroidal compound with a defined stereochemistry, serving as a critical intermediate in advanced pharmaceutical synthesis. Its precise molecular architecture makes it an essential building block for the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of steroidal drugs and hormones.
• Research & Development: Used in medicinal chemistry for the discovery and development of new therapeutic agents targeting hormone receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Fine Chemical Synthesis: Building block for creating complex, stereochemically-defined molecules in custom synthesis and process development.
• Biochemical Research: Tool compound for studying steroid metabolism, enzyme inhibition, and related biochemical pathways.

Basic Information

Product Name	(8R,9S,13S,14S)-3,16-Dihydroxy-13-Methyl-7,8,9,11,12,14,15,16 Octahydro-6H-Cyclopenta[A]Phenanthren-17-One
CAS No.	966-06-3
Molecular Formula	C₁₈H₂₆O₃
Molecular Weight	290.40 g/mol
Synonyms	3,16α-Dihydroxy-13β-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one; 3,16α-Dihydroxy-13β-methyl-gona-1,3,5(10)-trien-17-one; 16α-Hydroxyestra-1,3,5(10)-triene-3,17-dione; 16α-Hydroxy-13β-methyl-3-hydroxygona-1,3,5(10)-trien-17-one; Estra-1,3,5(10)-triene-3,16α-diol-17-one; 13β-Methyl-3,16α-dihydroxygona-1,3,5(10)-trien-17-one
EINECS	Contact for details

Quality Control

Our (8R,9S,13S,14S)-3,16-Dihydroxy-13-Methyl-7,8,9,11,12,14,15,16 Octahydro-6H-Cyclopenta[A]Phenanthren-17-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥98% by HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a dry environment and opened under conditions of low humidity to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (specified stereoisomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.