Description

Isoliquiritigenin CAS NO 961-29-5 is a bioactive flavonoid compound, a chalconoid derivative primarily isolated from the roots of *Glycyrrhiza* species (licorice). This compound is valued for its significant role as a key intermediate in biochemical pathways and for its diverse biological activities. It is a critical material for research and development in the pharmaceutical, nutraceutical, and cosmetic industries, where its antioxidant, anti-inflammatory, and potential chemopreventive properties are of high interest.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate for synthesizing novel drug candidates and as a reference standard for analytical studies.
• Nutraceutical & Dietary Supplements: Used in formulations targeting oxidative stress and inflammation due to its potent antioxidant properties.
• Cosmetic & Skincare Products: Incorporated into anti-aging and skin-brightening formulations for its ability to inhibit tyrosinase and protect against UV-induced damage.
• Biochemical Research: Employed as a tool compound to study cellular signaling pathways, enzyme inhibition (e.g., aldose reductase), and metabolic processes.
• Functional Food & Beverage Additives: Explored as a natural bioactive ingredient to enhance the health profile of food products.
• Reference Standard: Essential for quality control and analytical method development in laboratories, ensuring product identification and purity assessment.

Basic Information

Product Name	Isoliquiritigenin
CAS No.	961-29-5
Molecular Formula	C15H12O4
Molecular Weight	256.25 g/mol
Synonyms	4,2',4'-Trihydroxychalcone; 2',4,4'-Trihydroxychalcone; (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; Licorice Chalcone; ISL; NSC 349438; 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-, (E)-
EINECS	213-519-7

Quality Control

Our Isoliquiritigenin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and UV for identification, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.