Description

(S)-Phenylephrine Hydrochloride is the single enantiomer form of a potent and selective α1-adrenergic receptor agonist. This high-purity chiral compound is critical for applications requiring precise stereochemical control and predictable pharmacological activity. It is primarily utilized by the pharmaceutical industry for the development and manufacturing of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Active Pharmaceutical Ingredient (API) in enantiomerically pure nasal decongestants and ophthalmic solutions.
• Chiral intermediate in the synthesis of more complex pharmaceutical compounds targeting adrenergic pathways.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Key component in clinical research and pharmacological studies investigating α1-adrenoceptor activity.
• Starting material for the preparation of specialty salts and derivatives for drug formulation.
• Used in the development of diagnostic agents and in-vitro testing kits.

Basic Information

Product Name	(S)-Phenylephrine Hydrochloride
CAS No.	939-38-8
Molecular Formula	C9H14ClNO2
Molecular Weight	203.66 g/mol
Synonyms	(S)-(-)-Phenylephrine Hydrochloride; L-Phenylephrine Hydrochloride; (-)-m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride; (1R)-1-(3-Hydroxyphenyl)-2-(methylamino)ethanol hydrochloride; (R)-(-)-Phenylephrine HCl; Phenylephrine (S)-enantiomer hydrochloride; Neo-Synephrine (enantiomer) hydrochloride
EINECS	213-350-6

Quality Control

Our (S)-Phenylephrine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification, to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific pharmacopoeial standards such as USP or EP.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.5%
Chiral Purity (Enantiomeric Excess)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.