Description

L-Phenylephrine Bitartrate is a high-purity, synthetic adrenergic agonist and a key pharmaceutical intermediate. It is valued for its potent and selective α-1 adrenergic receptor activity, making it a critical component in the formulation of various medicinal products. This compound is essential for manufacturers in the pharmaceutical, biotechnology, and advanced research sectors requiring a reliable and consistent active pharmaceutical ingredient (API).

Application

• Pharmaceutical API: Primary use as the active ingredient in nasal decongestant sprays, eye drops (mydriatics), and formulations for hypotension.
• Ophthalmic Solutions: Used in eye examinations to dilate pupils and in treatments for conditions like red eye and glaucoma.
• Cardiovascular Research: A standard tool in pharmacological studies investigating α-adrenergic receptor function and vascular tone.
• Nasal Decongestants: Key component in over-the-counter and prescription medications for relief from sinus congestion and allergies.
• Vasopressor Agent: Employed in clinical settings to manage low blood pressure, particularly during spinal anesthesia.
• Analytical Reference Standard: Serves as a certified reference material (CRM) for quality control and method development in analytical laboratories.

Basic Information

Product Name	L-Phenylephrine Bitartrate
CAS No.	14787-58-7
Molecular Formula	C9H13NO2 • C4H6O6
Molecular Weight	317.27 g/mol
Synonyms	(-)-Phenylephrine Bitartrate; (R)-(-)-Phenylephrine Bitartrate; L-(-)-Phenylephrine Hydrogen Tartrate; Phenylephrine L-Bitartrate; (1R)-1-(3-Hydroxyphenyl)-2-(methylamino)ethanol (2R,3R)-2,3-dihydroxybutanedioate (1:1); m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol L-tartrate; Neo-Synephrine Bitartrate
EINECS	Contact for details

Quality Control

Our L-Phenylephrine Bitartrate is manufactured under strict quality systems to meet the rigorous standards of the pharmaceutical industry. Production adheres to current Good Manufacturing Practices (cGMP) guidelines, and the material is typically characterized against relevant pharmacopeial monographs (e.g., USP, EP). Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring full traceability and compliance for your regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	-50.0° to -56.0° (c=2 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.