Description

(-)-Phenylephrine Hydrogentartrate is the specific levorotatory enantiomer of the adrenergic agonist phenylephrine, formulated as its hydrogen tartrate salt for enhanced stability and handling. This high-purity chiral intermediate is critical for ensuring the precise pharmacological activity required in advanced pharmaceutical synthesis. It is primarily utilized by manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the research, development, and production of enantiomerically pure active pharmaceutical ingredients (APIs).

Application

• As a key chiral building block in the synthesis of enantiomerically pure pharmaceutical compounds.
• Primary raw material for the manufacture of (-)-Phenylephrine Hydrochloride, a widely used decongestant and vasopressor.
• Utilized in preclinical and clinical research for studying α-1 adrenergic receptor agonists.
• Intermediate in the production of specialized ophthalmic solutions requiring the specific (-)-enantiomer.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Starting material for novel drug discovery programs targeting cardiovascular and nasal decongestant therapies.

Basic Information

Product Name	(-)-Phenylephrine Hydrogentartrate
CAS No.	17162-39-9
Molecular Formula	C17H21NO7
Molecular Weight	351.35 g/mol
Synonyms	(-)-Phenylephrine Bitartrate; (R)-(-)-Phenylephrine Hydrogen Tartrate; L-Phenylephrine Hydrogen Tartrate; (1R)-1-(3-Hydroxyphenyl)-2-(methylamino)ethanol hydrogen L-(+)-tartrate; Phenylephrine L-Hydrogen Tartrate; (-)-m-Synephrine Hydrogen Tartrate; Levophenylephrine Hydrogen Tartrate
EINECS	Contact for details

Quality Control

Our (-)-Phenylephrine Hydrogentartrate is manufactured under strict quality management systems. We offer material suitable for pharmaceutical applications, with quality attributes tailored to meet customer-specific requirements. Certificates of Analysis (COA) documenting identity, purity, enantiomeric excess, and related substances are provided with each batch to ensure full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.