Description

cis-3,3-Dimethylcyclopropane-1,2-Dicarboxylic Acid is a high-purity, versatile cyclopropane-based dicarboxylic acid derivative. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is essential for R&D chemists and manufacturers in the pharmaceutical and agrochemical industries, where its rigid, strained-ring structure imparts unique biological and physical properties to target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring chiral, constrained carboxylic acid motifs.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used to create chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Monomer for producing specialty polyesters and polyamides with specific thermal and mechanical properties.
• Fine Chemical Production: Intermediate in the manufacture of flavors, fragrances, and advanced materials.
• Academic & Industrial R&D: Valuable reagent for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	cis-3,3-Dimethylcyclopropane-1,2-Dicarboxylic Acid
CAS No.	936-87-8
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	(1R,2S)-rel-3,3-Dimethylcyclopropane-1,2-dicarboxylic Acid; (1S,2R)-rel-3,3-Dimethylcyclopropane-1,2-dicarboxylic Acid; cis-3,3-Dimethyl-1,2-cyclopropanedicarboxylic Acid; NSC 163044; 3,3-Dimethylcyclopropane-1,2-dicarboxylic Acid; (±)-cis-3,3-Dimethylcyclopropane-1,2-dicarboxylic Acid; rac-cis-3,3-Dimethylcyclopropane-1,2-dicarboxylic Acid
EINECS	Contact for details

Quality Control

Our cis-3,3-Dimethylcyclopropane-1,2-Dicarboxylic Acid is produced under a strict quality management system. Every batch undergoes rigorous analytical testing including HPLC, NMR, and chiral purity analysis to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request. We support custom synthesis and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and potential degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.