Description

1-Thia-4-Azaspiro[4.5]Decane Hydrochloride is a high-purity organic salt compound, recognized for its role as a key synthetic intermediate in advanced pharmaceutical research and development. Its value lies in providing a reliable and structurally defined building block for the synthesis of complex molecules, particularly those with spirocyclic or heterocyclic frameworks. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate and scale new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) or possessing spirocyclic architectures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the spirocyclic moiety can impart unique biological activity.
• Chemical Synthesis: Serves as a versatile precursor for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Ligand and Catalyst Development: Potential use in creating novel ligands for metal catalysis or as a scaffold for organocatalysts.
• Material Science Precursor: May be employed in the synthesis of specialty polymers or organic electronic materials requiring specific nitrogen and sulfur heteroatom integration.

Basic Information

Product Name	1-Thia-4-Azaspiro[4.5]Decane Hydrochloride
CAS No.	933-41-5
Molecular Formula	C8H16ClNS
Molecular Weight	193.74 g/mol
Synonyms	1-Thia-4-azaspiro[4.5]decane hydrochloride; 1-Thia-4-azaspiro[4.5]decane, hydrochloride; 4-Thia-1-azaspiro[4.5]decane hydrochloride; Thiomorpholine, 4,4-pentamethylene-, hydrochloride; Spiro[4.5]decane, 1-thia-4-aza-, hydrochloride; 4,4-Pentamethylenethiomorpholine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Thia-4-Azaspiro[4.5]Decane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.