Description

Ethyl Glyoxalate CAS NO 924-44-7 is a versatile and highly reactive ester of glyoxylic acid, serving as a crucial building block in organic synthesis. Its value lies in its bifunctional nature, featuring both an aldehyde and an ester group, which enables its use in a wide array of condensation, cyclization, and multi-step reactions. This compound is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to synthesize complex heterocycles, active pharmaceutical ingredients (APIs), and advanced intermediates.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of various heterocyclic compounds, including imidazoles, pyrazines, and other nitrogen-containing structures found in APIs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, where it introduces critical functional groups.
• Fine Chemical & Flavor/Fragrance Industry: Employed in the manufacture of complex aroma chemicals and specialty flavors due to its reactive carbonyl functionality.
• Cross-Coupling & Condensation Reactions: Acts as an electrophile in reactions such as the Knoevenagel condensation and other C-C bond-forming processes.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and novel molecular entities.

Basic Information

Product Name	Ethyl Glyoxalate
CAS No.	924-44-7
Molecular Formula	C4H6O3
Molecular Weight	102.09 g/mol
Synonyms	Ethyl 2-oxoacetate; Glyoxylic acid ethyl ester; Oxoacetic acid ethyl ester; Ethyl oxoacetate; Ethyl glyoxylate; Ethyl 2-oxoethanoate; Ethyl formylformate; Acetic acid, 2-oxo-, ethyl ester
EINECS	213-108-3

Quality Control

Our Ethyl Glyoxalate is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical testing, including Gas Chromatography (GC) and Nuclear Magnetic Resonance (NMR) spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.