Description

Acetylphosphonic Acid Diethyl Ester is a versatile organophosphorus compound that serves as a key synthetic intermediate. Its value lies in its ability to act as a phosphorylating agent and a precursor for more complex phosphorus-containing molecules. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those with phosphate or phosphonate bioisosteres for improved metabolic stability.
• Agrochemical Synthesis: Serves as a building block for creating herbicides, insecticides, and plant growth regulators containing phosphonate groups.
• Ligand and Catalyst Preparation: Employed in the development of specialized phosphine ligands for transition metal catalysis and coordination chemistry.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the synthesis of flame-retardant polymers and specialty coatings.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in organic and medicinal chemistry for constructing C-P bonds.

Basic Information

Product Name	Acetylphosphonic Acid Diethyl Ester
CAS No.	919-19-7
Molecular Formula	C6H13O4P
Molecular Weight	180.14 g/mol
Synonyms	Diethyl Acetylphosphonate; Diethyl (Acetyl)phosphonate; Acetylphosphonic Acid Diethyl Ester; (Acetyl)phosphonic Acid Diethyl Ester; Diethoxyphosphinylmethyl Methyl Ketone; Acetylphosphonate Diethyl Ester; Ethyl Acetylphosphonate; EINECS 213-051-4
EINECS	213-051-4

Quality Control

Our Acetylphosphonic Acid Diethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including purity assay and impurity profiling, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.