Description

Primaquine is a synthetic 8-aminoquinoline derivative, recognized globally as a critical pharmaceutical active ingredient. Its primary commercial value lies in its potent antimalarial activity, specifically targeting the dormant hypnozoite stage of *Plasmodium vivax* and *Plasmodium ovale* parasites to prevent relapse. This compound is essential for manufacturers in the pharmaceutical industry producing anti-malarial medications, as well as for research institutions focused on parasitology and drug development.

Application

• Pharmaceutical Manufacturing: Primary use as the active pharmaceutical ingredient (API) in anti-malarial tablets and combination therapies for radical cure.
• Relapse Prevention: Critical component in treatment regimens targeting the hypnozoite stages of *P. vivax* and *P. ovale* malaria.
• Research & Development: Used as a reference standard and biochemical tool in parasitology research, drug mechanism studies, and screening for new anti-malarial compounds.
• Clinical Formulations: Serves as a key ingredient in the development of various dosage forms, including immediate and sustained-release formulations.
• Public Health Programs: Supplied for use in large-scale malaria control and elimination initiatives by government and non-governmental organizations.

Basic Information

Product Name	Primaquine
CAS No.	90-34-6
Molecular Formula	C15H21N3O
Molecular Weight	259.35 g/mol
Synonyms	Primaquine Phosphate (common salt); Primaquine Diphosphate; 8-[(4-Amino-1-methylbutyl)amino]-6-methoxyquinoline; SN 13272; NSC 143164; Primaquin; Primaquina
EINECS	Contact for details

Quality Control

Our Primaquine is manufactured and tested under strict quality management systems. We provide material that meets or exceeds relevant pharmacopeial standards, including USP and EP monographs where applicable. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure supply reliability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.