Description

3-(4-Fluorophenyl)-1,4-Diazaspiro[4.5]Dec-3-Ene-2-Thione is a high-value, heterocyclic organic compound featuring a unique spirocyclic and thione functional group architecture. This specialized structure makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. The compound, identified by CAS No. 899926-67-1, is supplied under stringent quality controls to ensure batch-to-batch consistency for demanding applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Organic Synthesis Building Block: Utilized in complex multi-step organic syntheses due to its reactive thione and imine functionalities.
• Material Science Research: Investigated as a potential monomer or ligand for creating specialized polymers or coordination complexes.

Basic Information

Item	Information
Product Name	3-(4-Fluorophenyl)-1,4-Diazaspiro[4.5]Dec-3-Ene-2-Thione
CAS No.	899926-67-1
Molecular Formula	C15H17FN2S
Molecular Weight	276.37 g/mol
Synonyms	3-(4-Fluorophenyl)-1,4-diazaspiro[4.5]dec-3-ene-2-thione; 1,4-Diazaspiro[4.5]dec-3-ene-2-thione, 3-(4-fluorophenyl)-; 899926-67-1; 3-(p-Fluorophenyl)-1,4-diazaspiro[4.5]dec-3-ene-2-thione; 3-(4-Fluorophenyl)-1,4-diazaspiro[4.5]dec-3-ene-2-thiol (tautomer); Spirocyclic thione intermediate; Fluorophenyl diazaspirodecanethione
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Fluorophenyl)-1,4-Diazaspiro[4.5]Dec-3-Ene-2-Thione is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for your grade. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.