Description

3-[[5-(2,3-Dichlorophenyl)-1H-Tetrazol-1-Yl]Methyl]Pyridine Hydrochloride is a high-purity, non-racemic pharmaceutical intermediate of significant commercial importance. This compound is valued for its role as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high specificity. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the discovery and development of new crop protection agents, leveraging the tetrazole moiety for bioactivity.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker in the design of chemical probes for target identification and validation studies.
• Material Science Research: Investigated for its potential in creating novel polymers or coordination complexes with specific electronic properties.
• Contract Synthesis: Supplied to CDMOs for custom synthesis projects requiring this specific chiral or functionalized intermediate.

Basic Information

Product Name	3-[[5-(2,3-Dichlorophenyl)-1H-Tetrazol-1-Yl]Methyl]Pyridine Hydrochloride
CAS No.	899507-36-9
Molecular Formula	C13H10Cl3N5
Molecular Weight	350.61 g/mol
Synonyms	3-((5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl)methyl)pyridine hydrochloride; 3-[(5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl)methyl]pyridinium chloride; Pyridine, 3-[[5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl]methyl]-, hydrochloride (1:1); (5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl)(pyridin-3-yl)methane hydrochloride
EINECS	Contact for details

Quality Control

Our 3-[[5-(2,3-Dichlorophenyl)-1H-Tetrazol-1-Yl]Methyl]Pyridine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.