Description

Pyridine, 5-Bromo-2-(Difluoromethoxy)- is a high-value, halogenated pyridine derivative distinguished by its bromine and difluoromethoxy substituents, which confer unique reactivity and physicochemical properties. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands and catalysts used in cross-coupling and other metal-mediated reactions.
• Material Science: Employed in the research and development of advanced organic electronic materials and liquid crystals.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags due to its reactive halogen site for further functionalization.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Pyridine, 5-Bromo-2-(Difluoromethoxy)-
CAS No.	899452-26-7
Molecular Formula	C7H4BrF2NO
Molecular Weight	236.01 g/mol
Synonyms	5-Bromo-2-(difluoromethoxy)pyridine; 2-(Difluoromethoxy)-5-bromopyridine; 5-Bromo-2-difluoromethoxypyridine; Pyridine, 5-bromo-2-[(difluoro)methoxy]-; 899452-26-7; 5-Br-2-(OCHF2)Pyridine
EINECS	Contact for details

Quality Control

Our Pyridine, 5-Bromo-2-(Difluoromethoxy)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP and research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.