Description

5-Chloro-3-Nitropyridine-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical precursor for developing novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular modifications. Pharmaceutical, agrochemical, and specialty chemical R&D teams need it to synthesize complex molecules, particularly for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated nitropyridine core.
• Ligand & Catalyst Development: Serves as a precursor for creating complex ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new chemical entities.

Basic Information

Product Name	5-Chloro-3-Nitropyridine-2-Carboxylic Acid
CAS No.	899423-94-0
Molecular Formula	C6H3ClN2O4
Molecular Weight	202.55 g/mol
Synonyms	2-Pyridinecarboxylic acid, 5-chloro-3-nitro-; 5-Chloro-3-nitro-2-pyridinecarboxylic acid; 5-Chloro-3-nitropicolinic acid; 3-Nitro-5-chloropyridine-2-carboxylic acid; 899423-94-0; Picolinic acid, 5-chloro-3-nitro-; 5-Chloro-3-nitropyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Nitropyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, including pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.