Description

6-Chloro-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is critical for the synthesis of complex molecules, offering a reactive aldehyde group and a halogenated pyrazolopyridine core for targeted derivatization. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Synthesis Scaffold: Used in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies due to its modifiable functional groups.
• Material Science Research: Investigated as a precursor for organic electronic materials and ligands in catalytic systems.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory synthetic chemistry and method development.

Basic Information

Product Name	6-Chloro-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbaldehyde
CAS No.	898911-37-0
Molecular Formula	C9H6ClN3O
Molecular Weight	207.62 g/mol
Synonyms	6-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxaldehyde; 1-Methyl-6-chloro-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde; 898911-37-0; 6-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde; Pyrazolo[3,4-b]pyridine-5-carbaldehyde, 6-chloro-1-methyl-
EINECS	Contact for details

Quality Control

Our 6-Chloro-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.