Description

5-[4-(Trifluoromethoxy)Phenyl]Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethoxy-substituted aromatic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted bioactivity and metabolic stability. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing next-generation products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides with enhanced efficacy and environmental profiles.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalytic and material science applications.
• Fluorinated Compound Library: An essential component for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	5-[4-(Trifluoromethoxy)Phenyl]Nicotinic Acid
CAS No.	898796-62-8
Molecular Formula	C13H8F3NO3
Molecular Weight	283.20 g/mol
Synonyms	5-[4-(Trifluoromethoxy)phenyl]pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-[4-(trifluoromethoxy)phenyl]-; Nicotinic acid, 5-[4-(trifluoromethoxy)phenyl]-; 5-(4-Trifluoromethoxyphenyl)nicotinic acid; 898796-62-8; 5-(4-(Trifluoromethoxy)phenyl)nicotinic acid
EINECS	Contact for details

Quality Control

Our 5-[4-(Trifluoromethoxy)Phenyl]Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.