Description

3',5'-Dichloro-3-(2,4-Dimethylphenyl)Propiophenone is a specialized aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chlorinated and dimethylphenyl motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its dichloro and dimethylphenyl groups contribute to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, or polymers with tailored electronic or optical properties.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Used in exploratory chemistry within university laboratories and corporate R&D centers for method development and novel compound library generation.

Basic Information

Product Name	3',5'-Dichloro-3-(2,4-Dimethylphenyl)Propiophenone
CAS No.	898794-52-0
Molecular Formula	C17H16Cl2O
Molecular Weight	307.21 g/mol
Synonyms	1-(3,5-Dichlorophenyl)-3-(2,4-dimethylphenyl)-1-propanone; 3,5-Dichloro-3'-(2,4-dimethylphenyl)propiophenone; Propiophenone, 3',5'-dichloro-3-(2,4-dimethylphenyl)-; 3-(2,4-Dimethylphenyl)-1-(3,5-dichlorophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 3',5'-Dichloro-3-(2,4-Dimethylphenyl)Propiophenone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to minimize exposure to moisture and atmospheric oxygen. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.