Description

3'-(4-Methylpiperazinomethyl)-2-Trifluoromethylbenzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its benzophenone core functionalized with a trifluoromethyl group and a methylpiperazine moiety. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and scale-up of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent drug candidates, especially in neurological and psychiatric research.
• API Synthesis: Serves as a crucial scaffold for constructing complex molecules intended for clinical development and commercial manufacturing.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of investigational and approved drugs.
• Biochemical Research: Employed as a tool compound in biochemical assays and for probing specific biological pathways.

Basic Information

Product Name	3'-(4-Methylpiperazinomethyl)-2-Trifluoromethylbenzophenone
CAS No.	898789-01-0
Molecular Formula	C21H23F3N2O
Molecular Weight	376.42 g/mol
Synonyms	2-Trifluoromethyl-3'-(4-methylpiperazinomethyl)benzophenone; 3'-(4-Methyl-1-piperazinylmethyl)-2-(trifluoromethyl)benzophenone; 2-(Trifluoromethyl)-3'-(4-methylpiperazin-1-ylmethyl)benzophenone; Benzophenone, 3'-(4-methyl-1-piperazinylmethyl)-2-(trifluoromethyl)-; 898789-01-0; 3'-(N-Methylpiperazinomethyl)-2-trifluoromethylbenzophenone
EINECS	Contact for details

Quality Control

Our 3'-(4-Methylpiperazinomethyl)-2-Trifluoromethylbenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.