Description

5-(3-Acetoxybenzoyl)-2-Chloropyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct molecular structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by research institutions, pharmaceutical manufacturers, and specialty chemical companies engaged in the development of novel therapeutic agents and high-value chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Used in the production of complex, high-value specialty chemicals for agrochemical and material science applications.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Employed in university and institutional laboratories for methodological development and exploratory chemical synthesis.

Basic Information

Product Name	5-(3-Acetoxybenzoyl)-2-Chloropyridine
CAS No.	898786-47-5
Molecular Formula	C14H10ClNO3
Molecular Weight	275.69 g/mol
Synonyms	2-Chloro-5-(3-acetoxybenzoyl)pyridine; 3-Acetoxy-5-(2-chloropyridin-5-yl)phenyl methanone; 5-(3-Acetyloxybenzoyl)-2-chloropyridine; (3-Acetoxyphenyl)(2-chloro-5-pyridinyl)methanone; 898786-47-5; 5-(3-Acetoxybenzoyl)-2-chloropyridine; 2-Chloro-5-(3-acetyloxybenzoyl)pyridine
EINECS	Contact for details

Quality Control

Our 5-(3-Acetoxybenzoyl)-2-Chloropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.