Description

3-(3-Acetoxybenzoyl)-2-Chloropyridine is a high-purity, advanced pharmaceutical intermediate characterized by its specific benzoylpyridine structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a reliable building block for research and development. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Active Pharmaceutical Ingredient (API) Development: Used in the development and scale-up processes for new APIs, especially those with pyridine-based structures.
• Chemical Synthesis: Employed in organic synthesis for the preparation of more complex molecules in academic and industrial R&D settings.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	3-(3-Acetoxybenzoyl)-2-Chloropyridine
CAS No.	898786-38-4
Molecular Formula	C14H10ClNO3
Molecular Weight	275.69 g/mol
Synonyms	2-Chloro-3-(3-acetoxybenzoyl)pyridine; 3-Acetoxy-3'-chloro-2,3'-bipyridine-5'-carboxaldehyde (incorrect but related); (3-Acetoxyphenyl)(2-chloropyridin-3-yl)methanone; 898786-38-4; 3-(3-Acetyloxybenzoyl)-2-chloropyridine
EINECS	Contact for details

Quality Control

Our 3-(3-Acetoxybenzoyl)-2-Chloropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.