Description

1-(2-Chloro-Pyridin-4-Yl)-2-Ethyl-Butan-1-One is a high-purity organic intermediate featuring a chloropyridine moiety and a ketone functional group. This compound is valued for its role as a versatile building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research and development chemists and process scale-up teams for creating active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Serves as a critical precursor in the manufacture of advanced herbicides and insecticides, leveraging the bioactivity of the chloropyridine structure.
• Chemical Research & Development: Used in academic and industrial R&D labs for method development, structure-activity relationship (SAR) studies, and exploring new chemical entities.
• Material Science: Potential application as a monomer or functional additive in the development of specialty polymers and advanced organic materials.

Basic Information

Product Name	1-(2-Chloro-Pyridin-4-Yl)-2-Ethyl-Butan-1-One
CAS No.	898785-69-8
Molecular Formula	C11H14ClNO
Molecular Weight	211.69 g/mol
Synonyms	2-Ethyl-1-(2-chloropyridin-4-yl)butan-1-one; 1-(2-Chloro-4-pyridinyl)-2-ethyl-1-butanone; 2-Chloro-4-(2-ethylbutyryl)pyridine; 4-(2-Ethylbutanoyl)-2-chloropyridine; 2-Ethylbutyryl-2-chloropyridine; α-Ethyl-2-chloroisonicotinoylpropane
EINECS	Contact for details

Quality Control

Our production of 1-(2-Chloro-Pyridin-4-Yl)-2-Ethyl-Butan-1-One adheres to stringent in-process controls and final batch testing to ensure consistent purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality management system is designed to support cGMP and ISO standards for traceability and reliability, making this intermediate suitable for demanding regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.