Description

4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-4'-Iodobutyrophenone is a specialized iodinated ketone derivative featuring a protected diol moiety, making it a valuable synthetic intermediate in advanced organic chemistry. Its core value proposition lies in its unique molecular architecture, which enables the controlled introduction of iodine and carbonyl functionality for constructing complex pharmacophores and materials. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in drug discovery, ligand synthesis, and the development of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or as a precursor for radioiodination in diagnostic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators where the iodine atom and ketone group are crucial for biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands in transition metal catalysis or organocatalysts due to its modifiable functional groups.
• Material Science Precursor: Employed in the research and development of organic electronic materials, liquid crystals, or polymers where its aromatic and halogenated structure can influence material properties.
• Chemical Biology Probe Development: Utilized for synthesizing molecular probes and tags for studying biological processes, leveraging the reactivity of the iodine for further functionalization.
• Academic and R&D Laboratories: A critical reagent for methodological development in organic synthesis, including cross-coupling reactions and protecting group chemistry.

Basic Information

Item	Details
Product Name	4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-4'-Iodobutyrophenone
CAS No.	898785-58-5
Molecular Formula	C₁₆H₂₁IO₃
Molecular Weight	388.24 g/mol
Synonyms	4'-Iodo-4-(5,5-dimethyl-1,3-dioxan-2-yl)butyrophenone; 1-[4-Iodophenyl]-4-(5,5-dimethyl-1,3-dioxan-2-yl)butan-1-one; 4-(5,5-Dimethyl-1,3-dioxan-2-yl)-1-(4-iodophenyl)butan-1-one; Butan-1-one, 1-(4-iodophenyl)-4-(5,5-dimethyl-1,3-dioxan-2-yl)-; 898785-58-5
EINECS	Contact for details

Quality Control

Our 4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-4'-Iodobutyrophenone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing results from HPLC, NMR, and other relevant tests is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.