Description

(2-Chloro-Pyridin-4-Yl)-Cyclopropyl-Methanone CAS NO 898785-12-1 is a high-value, multi-functional heterocyclic building block featuring a chloropyridine core and a cyclopropyl ketone moiety. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules with tailored properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated pyridine structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers due to its conjugated system.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Utilized in exploratory chemistry for library synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	(2-Chloro-Pyridin-4-Yl)-Cyclopropyl-Methanone
CAS No.	898785-12-1
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	Cyclopropyl(2-chloropyridin-4-yl)methanone; 2-Chloro-4-cyclopropanoylpyridine; 4-Acetyl-2-chloropyridine, cyclopropyl analog; (2-Chloro-4-pyridinyl)cyclopropylmethanone; 898785-12-1; 2-Chloropyridin-4-yl cyclopropyl ketone; 4-(Cyclopropanecarbonyl)-2-chloropyridine
EINECS	Contact for details

Quality Control

Every batch of (2-Chloro-Pyridin-4-Yl)-Cyclopropyl-Methanone is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.