Description

2-Chloro-4-(4-Chlorobutyryl)Pyridine is a high-purity, multi-functional organic building block characterized by its reactive chlorinated pyridine and ketone functionalities. This compound is of significant value in advanced organic synthesis, serving as a versatile precursor for constructing complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing antimicrobial properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Custom Synthesis and Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D programs.

Basic Information

Product Name	2-Chloro-4-(4-Chlorobutyryl)Pyridine
CAS No.	898785-06-3
Molecular Formula	C9H9Cl2NO
Molecular Weight	218.08 g/mol
Synonyms	4-(4-Chlorobutanoyl)-2-chloropyridine; 1-(2-Chloropyridin-4-yl)-4-chlorobutan-1-one; 2-Chloro-4-(4-chloro-1-oxobutyl)pyridine; 4-Chlorobutyryl 2-chloropyridin-4-yl ketone; 898785-06-3; Butan-1-one, 1-(2-chloro-4-pyridinyl)-4-chloro-; 2-Chloro-4-(γ-chlorobutyryl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(4-Chlorobutyryl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.