Description

Ethyl 7-[2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Phenyl]-7-Oxoheptanoate is a high-purity synthetic intermediate featuring a complex molecular architecture that combines a spirocyclic ketal-protected amine with a keto-ester functional chain. This compound is valued for its role as a key building block in advanced organic synthesis, particularly for constructing pharmacologically active molecules. It is primarily sought by pharmaceutical R&D and fine chemical synthesis laboratories for the development of new therapeutic agents and other specialized organic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological or metabolic pathways.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors, where its structural motifs can mimic peptide substrates.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme function and cellular signaling processes.
• Peptidomimetic Synthesis: The spirocyclic and keto-ester groups make it valuable for constructing non-peptide compounds that mimic peptide structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-complexity intermediates.
• Academic & Industrial R&D: Utilized in research institutions and corporate R&D centers for exploratory chemistry and new molecule library generation.

Basic Information

Item	Detail
Product Name	Ethyl 7-[2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Phenyl]-7-Oxoheptanoate
CAS No.	898781-32-3
Molecular Formula	C24H35NO5
Molecular Weight	417.54 g/mol
Synonyms	Ethyl 7-oxo-7-{2-[(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl]phenyl}heptanoate; 898781-32-3; Ethyl 7-(2-((1,4-Dioxa-8-azaspiro[4.5]decan-8-yl)methyl)phenyl)-7-oxoheptanoate; 7-Oxoheptanoic acid, 7-[2-[(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]phenyl]-, ethyl ester; UNII-7Z7S8A7W4F; AS-81033; SCHEMBL21808431; ZINC000006889676
EINECS	Contact for details

Quality Control

Our Ethyl 7-[2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Phenyl]-7-Oxoheptanoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant industry guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is stable under these conditions but should be kept away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere packaging to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.