Description

Ethyl 5-[2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Phenyl]-5-Oxovalerate is a high-value, complex organic intermediate featuring a spirocyclic acetal-protected amine and a keto-ester functional group. This compound matters for its role as a versatile building block in the synthesis of advanced pharmaceutical agents and fine chemicals, enabling the construction of sophisticated molecular architectures. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the preparation of advanced, high-performance crop protection agents and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers or organic electronic materials requiring specific functional group integration.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical component for custom synthesis houses serving the life sciences sector with complex, multi-step organic molecules.

Basic Information

Product Name	Ethyl 5-[2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Phenyl]-5-Oxovalerate
CAS No.	898781-26-5
Molecular Formula	C22H31NO5
Molecular Weight	389.49 g/mol
Synonyms	Ethyl 5-(2-((1,4-Dioxa-8-azaspiro[4.5]decan-8-yl)methyl)phenyl)-5-oxopentanoate; 5-Oxovaleric acid, 5-[2-[(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)methyl]phenyl]-, ethyl ester; Ethyl 5-(2-((8-Methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl)phenyl)-5-oxopentanoate (alternative numbering); Keto-ester spirocyclic amine intermediate; CAS 898781-26-5
EINECS	Contact for details

Quality Control

Our Ethyl 5-[2-[8-(1,4-Dioxa-8-Azaspiro[4.5]Decyl)Methyl]Phenyl]-5-Oxovalerate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.