Description

2-(2-Trifluoromethylbenzoyl)Pyridine is a high-value, fluorinated aromatic ketone building block with the CAS number 898779-76-5. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals due to the unique electronic properties imparted by the trifluoromethyl group. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used as a precursor for novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in catalysis and material science applications.
• Organic Electronic Materials: Potential use in the synthesis of advanced materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research: Employed in academic and industrial laboratories for method development and exploring new fluorination chemistry and cross-coupling reactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Product Name	2-(2-Trifluoromethylbenzoyl)Pyridine
CAS No.	898779-76-5
Molecular Formula	C13H8F3NO
Molecular Weight	251.21 g/mol
Synonyms	2-(2-(Trifluoromethyl)benzoyl)pyridine; 2-Pyridinyl[2-(trifluoromethyl)phenyl]methanone; o-(Trifluoromethyl)benzoylpyridine; 2-(α,α,α-Trifluoro-o-toluoyl)pyridine; 2-(2-Trifluoromethyl-benzoyl)-pyridine; (2-Trifluoromethylphenyl)(pyridin-2-yl)methanone; 898779-76-5 (CAS)
EINECS	Contact for details

Quality Control

Our 2-(2-Trifluoromethylbenzoyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.