Description

2-(2,5-Dichlorobenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiophene-based molecular architecture. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical manufacturers and R&D organizations focused on creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Serves as a building block for creating novel crop protection agents and pesticides with specific activity profiles.
• Material Science Research: Used in the development of organic semiconductors and conductive polymers due to its thiophene core.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new heterocyclic chemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals for clients.

Basic Information

Product Name	2-(2,5-Dichlorobenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene
CAS No.	898778-90-0
Molecular Formula	C14H10Cl2O3S
Molecular Weight	329.20 g/mol
Synonyms	5-(1,3-Dioxolan-2-yl)-2-(2,5-dichlorobenzoyl)thiophene; 2-(2,5-Dichlorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene; Thiophene, 2-(2,5-dichlorobenzoyl)-5-(1,3-dioxolan-2-yl)-; 898778-90-0; 2,5-Dichloro-α-oxo-5-(1,3-dioxolan-2-yl)-2-thienylbenzenemethanol
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dichlorobenzoyl)-5-(1,3-Dioxolan-2-Yl)Thiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.