Description

Ethyl 4-Oxo-4-(2-Trifluoromethylphenyl)Butyrate is a high-purity organic ester building block featuring a trifluoromethylphenyl moiety, a key structural motif valued for its ability to modulate the physicochemical properties of target molecules. This compound is essential for research and development chemists seeking to introduce lipophilicity and metabolic stability into novel chemical entities. It is primarily utilized in the pharmaceutical and agrochemical industries as a critical intermediate in the synthesis of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that require fluorinated aromatic components for improved performance.
• Chemical Development: Employed in process chemistry for scaling up the production of complex, fluorinated organic molecules.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs in universities and contract research organizations (CROs).

Basic Information

Item	Details
Product Name	Ethyl 4-Oxo-4-(2-Trifluoromethylphenyl)Butyrate
CAS No.	898777-67-8
Molecular Formula	C13H13F3O3
Molecular Weight	274.24 g/mol
Synonyms	Ethyl 4-oxo-4-[2-(trifluoromethyl)phenyl]butanoate; 4-Oxo-4-(2-trifluoromethylphenyl)butyric Acid Ethyl Ester; Ethyl 4-(2-Trifluoromethylbenzoyl)butyrate; Butanoic acid, 4-oxo-4-[2-(trifluoromethyl)phenyl]-, ethyl ester; 898777-67-8
EINECS	Contact for details

Quality Control

Our Ethyl 4-Oxo-4-(2-Trifluoromethylphenyl)Butyrate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.