Description

Ethyl 5-(4-Iodophenyl)-5-Oxovalerate is a high-purity organic building block characterized by its iodophenyl and keto ester functional groups. This compound is a critical intermediate for the synthesis of complex molecules in pharmaceutical and advanced material research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or plant growth regulators that leverage the iodophenyl moiety.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for creating advanced organic electronic materials due to its rigid aromatic core and functional handles for further modification.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create more complex biaryl structures.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes.
• Academic & Contract Research: A valuable reagent for university laboratories and CROs (Contract Research Organizations) exploring new synthetic methodologies.

Basic Information

Product Name	Ethyl 5-(4-Iodophenyl)-5-Oxovalerate
CAS No.	898777-42-9
Molecular Formula	C13H15IO3
Molecular Weight	346.16 g/mol
Synonyms	Ethyl 5-(4-iodobenzoyl)valerate; 5-(4-Iodobenzoyl)pentanoic Acid Ethyl Ester; Ethyl 5-(p-Iodobenzoyl)valerate; 4-Iodophenyl 5-ethoxy-5-oxopentyl ketone; 898777-42-9; Ethyl 4-(4-Iodobenzoyl)butyrate (common misnomer); 5-Oxo-5-(4-iodophenyl)pentanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-(4-Iodophenyl)-5-Oxovalerate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.