Description

Ethyl 4-(4-Iodophenyl)-4-Oxobutyrate is a high-purity organic building block characterized by its iodophenyl and oxobutyrate functional groups. This compound is critical for facilitating advanced synthetic pathways in pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the iodine atom for further functionalization.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts due to its reactive carbonyl and aryl iodide moieties.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of advanced polymers with specific optical or electronic properties.
• Chemical Biology Probe Development: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Academic and Institutional Research: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and carbonyl chemistry.

Basic Information

Product Name	Ethyl 4-(4-Iodophenyl)-4-Oxobutyrate
CAS No.	898777-39-4
Molecular Formula	C12H13IO3
Molecular Weight	332.14 g/mol
Synonyms	4-(4-Iodobenzoyl)butyric Acid Ethyl Ester; Ethyl 4-(4-Iodobenzoyl)butyrate; 4-Oxo-4-(4-iodophenyl)butanoic Acid Ethyl Ester; Ethyl γ-Oxo-4-iodohydrocinnamate; 898777-39-4; Butanoic acid, 4-oxo-4-(4-iodophenyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4-(4-Iodophenyl)-4-Oxobutyrate is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency meet the exacting standards required for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.