Description

Ethyl 5-Oxo-6,6,6-Trifluorohexanoate is a high-value fluorinated ketoester building block, essential for introducing the trifluoromethyl group into complex molecular architectures. Its unique structure offers significant advantages in modulating the lipophilicity, metabolic stability, and binding affinity of target compounds. This intermediate is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the CF3 group enhances biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or modifier for creating specialty polymers with tailored surface properties and chemical resistance.
• Liquid Crystal & OLED Materials: Employed in the development of fluorinated components for electronic display and lighting technologies.
• Organic Synthesis Reagent: A versatile reagent for nucleophilic addition and condensation reactions in complex organic synthesis.
• Fluorine Chemistry Research: Critical material for academic and industrial research exploring new methodologies in fluoroorganic chemistry.

Basic Information

Product Name	Ethyl 5-Oxo-6,6,6-Trifluorohexanoate
CAS No.	898776-52-8
Molecular Formula	C8H11F3O3
Molecular Weight	212.17 g/mol
Synonyms	5-Oxo-6,6,6-trifluorohexanoic Acid Ethyl Ester; Ethyl 6,6,6-Trifluoro-5-oxohexanoate; 6,6,6-Trifluoro-5-oxo-hexanoic Acid Ethyl Ester; 5-Oxo-6,6,6-trifluoro-hexanoic Acid Ethyl Ester; Ethyl 5-Oxo-6,6,6-trifluorohexanoate; Hexanoic acid, 5-oxo-6,6,6-trifluoro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Oxo-6,6,6-Trifluorohexanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.