Description

Ethyl 5-Oxo-5-[2-(Pyrrolidinomethyl)Phenyl]Valerate is a high-purity organic compound with the CAS number 898775-30-9, serving as a critical advanced intermediate in modern pharmaceutical synthesis. Its molecular structure, featuring both ester and pyrrolidine moieties, makes it a versatile building block for constructing complex active pharmaceutical ingredients (APIs). This product is essential for research and development chemists and production facilities focused on creating innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• API Synthesis: Used in the multi-step production of complex Active Pharmaceutical Ingredients (APIs) requiring specific chiral or functionalized frameworks.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Process Chemistry Development: Serves as a standard or starting material for scaling up synthetic routes from laboratory to pilot and commercial production.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of proprietary compounds under cGMP conditions.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	Ethyl 5-Oxo-5-[2-(Pyrrolidinomethyl)Phenyl]Valerate
CAS No.	898775-30-9
Molecular Formula	C18H25NO3
Molecular Weight	303.40 g/mol
Synonyms	Ethyl 5-Oxo-5-(2-(pyrrolidin-1-ylmethyl)phenyl)pentanoate; 5-Oxo-5-[2-(1-pyrrolidinylmethyl)phenyl]pentanoic Acid Ethyl Ester; Ethyl 5-(2-(Pyrrolidin-1-ylmethyl)phenyl)-5-oxopentanoate; 898775-30-9; Pentanoic acid, 5-oxo-5-[2-(1-pyrrolidinylmethyl)phenyl]-, ethyl ester; Ethyl 5-oxo-5-(2-(pyrrolidin-1-ylmethyl)phenyl)valerate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-Oxo-5-[2-(Pyrrolidinomethyl)Phenyl]Valerate is manufactured and tested under a strict quality management system to ensure consistency and reliability for critical pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, with testing performed using validated methods such as HPLC, GC, and NMR. Our quality commitment aligns with ICH guidelines, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with good laboratory and manufacturing practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.