Description

3-Chloro-4-Fluoro-4'-Piperidinomethyl Benzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its benzophenone core substituted with halogen and piperidine groups. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of therapeutic agents, particularly within central nervous system (CNS) and other specialty drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• CNS Drug Development: Used in the research and production of potential therapeutics targeting neurological disorders.
• Chemical Synthesis: Employed in organic synthesis for introducing specific halogenated benzophenone motifs into larger molecular architectures.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-Chloro-4-Fluoro-4'-Piperidinomethyl Benzophenone
CAS No.	898775-23-0
Molecular Formula	C19H19ClFNO
Molecular Weight	331.81 g/mol
Synonyms	4'-(Chloromethyl)-3-fluoro-4-piperidinobenzophenone; 4'-(Piperidinomethyl)-3-chloro-4-fluorobenzophenone; Benzophenone, 3-chloro-4-fluoro-4'-(piperidinomethyl)-; 898775-23-0; 3-Chloro-4-fluoro-4'-(piperidinomethyl)benzophenone
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluoro-4'-Piperidinomethyl Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.